Early detection of population fragmentation using linkage disequilibrium estimation of effective population size
نویسندگان
چکیده
منابع مشابه
Recent human effective population size estimated from linkage disequilibrium.
Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present the first genome-wide estimates of human effective population size from LD data. Chromosome-specific effective population size was estimated for all autosomes and the X chromosome from estimated LD between SNP pairs <100 kb apart. We accoun...
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Use of single-sample genetic methods to estimate effective population size has skyrocketed in recent years. Although the underlying models assume discrete generations, they are widely applied to age-structured species. We simulated genetic data for 21 iteroparous animal and plant species to evaluate two untested hypotheses regarding performance of the single-sample method based on linkage diseq...
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ژورنال
عنوان ژورنال: Conservation Genetics
سال: 2010
ISSN: 1566-0621,1572-9737
DOI: 10.1007/s10592-010-0112-x